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What is eczema? Eczema is a general term for a group of conditions that cause the skin to become inflamed, red, dry, bumpy, and itchy. However, this term is most often used to refer to a condition called atopic dermatitis. In atopic dermatitis , skin barrier function (the "glue" of the skin) is damaged. This loss of barrier function. Everyone we talked to could name at least one trigger which could make their eczema worse, and many different triggers were mentioned. This included people who also had asthma, allergies and/or hay fever (linked with 'atopic eczema'). What might be a problem for one person could be completely fine for another. 12 Feb Atopic eczema is a chronic, relapsing, inflammatory skin condition characterised by an itchy red rash that favours the skin creases such as the folds of.
By Stephen Matthews For Mailonline.
here A cure for eczema could be in the pipeline after researchers have figured out what may be responsible for causing it. For years, scientists have been unsure as to what actually triggers the common skin condition that plagues millions.
Those affected have instead been given creams aimed at relieving their red, cracked and itchy skin symptoms. But new research from Newcastle University offers hope of an eventual treatment targeting the root cause - not just the symptoms. They discovered that sufferers are missing a vital protein called filaggrin in their skin.
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This then drives the development of the debilitating condition, which affects around one in ten adults in the UK. Lead author Professor Nick Reynolds said: Researchers tested human skin models that were lacking filaggrin for the study which was published in the Journal of Allergy and Clinical Immunology. They found that removing the protein triggered the same genetic signals as those who suffer from eczema.
These included inflammation of the skin, breakdown of cell structure and stress response - which all cause the condition, they noted. The findings allow for scientists to get a better understanding of the condition, opening up a potential route for a cure.
Abid talks about using rubber gloves for washing up to avoid getting his hands too wet. In the most part, allergies develop on the background of bad eczema. We know that the standard atopic dermatitis treatment includes:
Researchers are hopeful there findings could lead to an eventual treatment targeting the root cause - not just the symptoms. Dr Anjali Mahto, consultant dermatologist and British Skin Foundation spokesperson welcomed the findings. The new research builds on an important discovery made by scientists in Dundee back in They showed that lack of the protein filaggrin in the skin caused an inherited dry skin condition known as ichthyosis vulgaris.
They found that the protein keeps bacteria out, while keeping water in to prevent the skin from drying. Therefore a lack of filaggrin leads to dry and flaky skin, the researchers noted.
This has go here strongly linked to the development of atopic eczema, as well as other allergic diseases such as hayfever and asthma. Across the wider world, the condition is believed to affect around three per cent of adults, figures suggest. It's more common in children, often developing before their first birthday and often persists into adulthood. The severe itching has profound effects on well-being and can often lead to sleep disturbance.
Also called atopic dermatitis, the condition causes distressing itchy lesions that can lead to broken skin with increased susceptibility to infection. It can have a severe impact on people's lives, work and sleep - but there is currently no cure. Conventional treatment with steroid creams can have side effects, and become less effective over time, which a natural therapy may avoid.
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Could a CURE for eczema be in sight? Experts finally discover what is triggering the skin condition after years of research For years, scientists have been unsure as to what triggers the skin condition Those affected have been given article source aimed at relieving their symptoms But new research offers hope of an eventual treatment targeting the root cause They discovered sufferers are missing a vital protein called filaggrin in their skin By Stephen Matthews For Mailonline Published: Share this article Share.
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Permethrin and ivermectin for scabies. J Clin Cell Immunol. Understanding and managing atopic dermatitis in adult patients. Conventional treatment with steroid creams can have side effects, and become less effective over time, which a natural therapy may avoid.
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Atopic Dermatitis in adults
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